The star has handed over the complete sum of his £25k honor prize money to the MVT, which operates to save the UK's small concert spaces.
He was presented with the award on mid-October as his new release People Watching was named the outstanding release of the past year.
Fender has chosen to donate the funds to the Music Venues Trust, in acknowledgment of the essential function local spots played in his beginning days.
"I wouldn't be doing what I am doing today if it hadn't been for all the shows I played around the North East, and further afield, when I was starting out," remarked Fender. "These spaces are iconic, but they are struggling."
Beginning in 2023, more than 150 of these spaces have shut down – about one-sixth of the total UK scene.
Recently, major artists like the band Pulp, Coldplay, the singer Katy Perry and Ed Sheeran have all supported the MVT in its attempts to keep the scene afloat, by including a modest fee to their ticket costs, which benefits independent venues.
Sam Fender also participated, collecting in excess of £100,000 on his live tour to help 38 small stages across England, Scotland, and Wales.
The donation assisted venues that were confronting potential shutdown due to issues arising from water damage, fires and family tragedies, as well as permit problems, court cases and sound issues.
Other venues obtained financial assistance in improving amenities and sound and lighting systems that helped musicians and audiences.
"The idea that revenue from shows in large arenas supports the smaller venues, where it all starts for musicians like me, is just sensible," the star has said.
He is among several artists to donate his honor winnings to worthy causes.
When the band earned the prize in the mid-90s for their record the album, frontman the singer stated that the group would give their winnings to the non-profit the charity.
In 2002, artist Ms Dynamite divided her award across several charities, such as the children's charity and a Sickle Cell organization.
"Additionally, I gave a grand to Highgate Newtown, to their gymnastics program, because I did gymnastics when I was a child and they needed updated gear," she explained to outlets.
In recent years, the band contributed their prize money to the local youth club that nurtured their group, in addition to other grassroots music organisations.
And 1994 winners M People donated their prize to a charity for MS after a friend was diagnosed the illness.
"The victory was quite enough," remarked artist Heather Small. "The money was the extra but we could do without the cherry, because we had the cake. So our winning impacted the lives of others."
Last week, the MVT shared it had protected a couple of local spots in that region, by placing them under community ownership.
One venue in that area and The Croft in the city were purchased under the Own Our Venues initiative, which is supported by Arts Council England and supporters who buy "stakes" in the properties.
